diff --git a/ViewModels/StationViewModel.cs b/ViewModels/StationViewModel.cs
index 70cb67b..29ca0ae 100644
--- a/ViewModels/StationViewModel.cs
+++ b/ViewModels/StationViewModel.cs
@@ -417,13 +417,17 @@ namespace TabletTester2025.ViewModels
 
             if (_isDissolution1Running)
             {
-                await ReadDissolutionChannelAsync(1);
+                if (ResolveDissolution1PercentAddress() != 0)
+                    await ReadDissolutionChannelAsync(1);
+
                 await CheckDissolutionSampleAsync(1);
             }
 
             if (_isDissolution2Running)
             {
-                await ReadDissolutionChannelAsync(2);
+                if (_plcConfig.Dissolution2Percent != 0)
+                    await ReadDissolutionChannelAsync(2);
+
                 await CheckDissolutionSampleAsync(2);
             }
 
@@ -432,12 +436,6 @@ namespace TabletTester2025.ViewModels
 
         private async Task CheckDissolutionSampleAsync(int channel)
         {
-            if (channel == 2 && _plcConfig.Dissolution2Percent == 0)
-            {
-                DissolutionCurveStatus = "溶出2溶出度寄存器未配置，未启用取样计算";
-                return;
-            }
-
             ushort coilAddress = channel == 1
                 ? _plcConfig.Dissolution1SampleAckCoil
                 : _plcConfig.Dissolution2SampleAckCoil;
@@ -448,8 +446,8 @@ namespace TabletTester2025.ViewModels
                 return;
             }
 
-            bool sampleConfirmed = await _plc.ReadCoilAsync(coilAddress);
-            if (sampleConfirmed)
+            bool sampleRequested = await _plc.ReadCoilAsync(coilAddress);
+            if (!sampleRequested)
             {
                 SetDissolutionSampleRequestActive(channel, false);
                 return;
@@ -458,13 +456,6 @@ namespace TabletTester2025.ViewModels
             if (IsDissolutionSampleRequestActive(channel) || IsDissolutionSamplePromptOpen(channel))
                 return;
 
-            if (GetNextPendingDissolutionSample(channel) == null)
-            {
-                await _plc.WriteCoilAsync(coilAddress, true);
-                DissolutionCurveStatus = $"溶出{channel}已完成全部取样点";
-                return;
-            }
-
             SetDissolutionSampleRequestActive(channel, true);
             SetDissolutionSamplePromptOpen(channel, true);
 
@@ -472,7 +463,8 @@ namespace TabletTester2025.ViewModels
             {
                 double percent = await ShowDissolutionSampleDialogAsync(channel);
                 RecordDissolutionSample(channel, percent);
-                await _plc.WriteCoilAsync(coilAddress, true);
+                await _plc.WriteCoilAsync(coilAddress, false);
+                SetDissolutionSampleRequestActive(channel, false);
                 LocalAlarm = $"溶出{channel}已记录取样结果";
                 DissolutionCurveStatus = "";
             }
@@ -1611,6 +1603,9 @@ namespace TabletTester2025.ViewModels
 
         private async Task StartDissolution1Async()
         {
+            if (_isDissolution1Running)
+                return;
+
             CurrentTest = TestType.Dissolution;
             Phase = TestPhase.Running;
             DissolutionPass = false;
@@ -1659,15 +1654,15 @@ namespace TabletTester2025.ViewModels
 
         private async Task StartDissolution2Async()
         {
+            if (_isDissolution2Running)
+                return;
+
             CurrentTest = TestType.Dissolution;
             Phase = TestPhase.Running;
             DissolutionPass = false;
             ResetDissolutionChannel(2);
             ResetDissolutionSampleState(2);
-            if (_plcConfig.Dissolution2Percent != 0)
-                CreateDissolutionSampleSchedule(2);
-            else
-                DissolutionCurveStatus = "溶出2溶出度寄存器未配置，仅执行设备控制，不保存计算结果";
+            CreateDissolutionSampleSchedule(2);
             _dissolution2StartTime = DateTime.Now;
             _isDissolution2Running = true;
             DissolutionPlotModel.Title = "溶出曲线";